{"id":90110,"date":"2020-11-17T00:00:00","date_gmt":"2020-11-16T13:00:00","guid":{"rendered":"https:\/\/www.fnarena.com\/index.php\/2020\/11\/17\/pharmabcine-to-present-the-final-data-of-phase-iia-rgbm-trial-at-sno-2020\/"},"modified":"2020-11-17T00:00:00","modified_gmt":"2020-11-16T13:00:00","slug":"pharmabcine-to-present-the-final-data-of-phase-iia-rgbm-trial-at-sno-2020","status":"publish","type":"post","link":"https:\/\/staging.fnarena.com\/index.php\/2020\/11\/17\/pharmabcine-to-present-the-final-data-of-phase-iia-rgbm-trial-at-sno-2020\/","title":{"rendered":"PharmAbcine to present the final data of Phase IIa rGBM trial at SNO 2020"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mma.prnasia.com\/media2\/1176198\/PharmAbcineLogo.jpg?p=medium600\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>DAEJEON,&#160;South Korea, <span class=\"xn-chron\">Nov. 16, 2020<\/span> \/PRNewswire\/ &#8212; PharmAbcine Inc. (KOSDAQ: 208340ks) announced today that the company will present the final results of the Phase IIa clinical trial of Olinvacimab for rGBM (recurrent glioblastoma multiforme) patients at SNO&#160;(Society of Neuro-Oncology) 2020.<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p><span id=\"spanHghltf03e\">The<\/span> clinical study was conducted in <span class=\"xn-location\">Australia<\/span> <span id=\"spanHghlta811\">from<\/span> 2016- 2017. &#160;<span id=\"spanHghlt333a\">In the study,<\/span> 25% of the patients had stable disease and 40% of the patients <span id=\"spanHghlt00ea\">had relief<\/span> from brain edema. The data from the study suggested <span id=\"spanHghlt37c7\">the<\/span>&#160;possibility of using Olinvacimab for rGBM patients who no longer respond to Avastin in treating severe brain edema.<\/p>\n<p>In 2017, PharmAbcine <span id=\"spanHghltdd61\">received approval<\/span> from <span id=\"spanHghltd3d9\">the<\/span> US FDA (Food and Drug Administration) for the Phase II clinical study of Olinvacimab for Avastin-refractory rGBM patients. Furthermore, Olinvacimab received Orphan Drug Designation (ODD) from both the US FDA and the Korean MFSD (Ministry of Food and Drug Safety) in 2018. <span id=\"spanHghltd77c\">Beginning<\/span> in 2019, the Phase II clinical trial is currently on-going.<\/p>\n<p>Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor with a fast growth rate. Recurrent glioblastoma multiforme (rGBM) is a disease in which the GBM recur after surgery and drug\/radiation therapy. It is known that rGBM has <span id=\"spanHghlt66be\">an<\/span> average life expectancy of about 4 months and causes extensive brain edema.<\/p>\n<p><b>About Society of Neuro-Oncology Annual Meeting<\/b><\/p>\n<p>Society of Neuro-Oncology Annual Meeting is the world&#8217;s largest neuro-oncology society held every year. This year <span class=\"xn-money\">marks 25<\/span><sup>th<\/sup> event with more than 2600 researchers and experts participating from more than 40 countries around the world. Through this event, many global pharmaceutical companies will present various cutting-edge technologies and advance their academic and research efforts in the field of neuro-oncology. SNO 2020 will be held virtually from&#160;November 19&#160;to 21.<\/p>\n<p><b>About PharmAbcine Inc.<\/b><\/p>\n<p>PharmAbcine is a clinical-stage biotech company focusing on the development of fully human antibody therapeutics to treat neovascular disorders, tumors, and other medically unmet diseases. It provides therapeutic antibodies for a wide spectrum of indications from&#160;oncology, immuno-oncology, ophthalmology, respiratory, to renal pathology.<\/p>\n<p>PharmAbcine has its own HuPhage library and innovative selection system. PharmAbcine&#8217;s advanced 3G expression system&#160;accommodates high levels of antibody production and steady reproducibility. With these cutting-edge technology platforms, it provides state of the art antibody generation services. <\/p>\n<p>For additional information about PharmAbcine, visit&#160;<a target=\"_blank\" href=\"http:\/\/www.pharmabcine.com\/\" rel=\"nofollow\">http:\/\/www.pharmabcine.com<\/a>. <\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2\">  <\/div>\n<p>Related Links :<\/p>\n<p>http:\/\/www.pharmabcine.com\/<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DAEJEON,&#160;South Korea, Nov. 16, 2020 \/PRNewswire\/ &#8212; PharmAbcine Inc. (KOSDAQ: 208340ks) announced today that the company will present the final&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[105],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/posts\/90110"}],"collection":[{"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/comments?post=90110"}],"version-history":[{"count":0,"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/posts\/90110\/revisions"}],"wp:attachment":[{"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/media?parent=90110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/categories?post=90110"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/staging.fnarena.com\/index.php\/wp-json\/wp\/v2\/tags?post=90110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}